Active NPI 1023550308 Individual Practitioner Female Practitioner

Angela Erin Knotts , FNP

Nurse Practitioner • Millsboro, DE

✓ Accepts Medicare Assignment

Professional Overview & Biography Verified Profile Summary

Angela Knotts, FNP is a certified Nurse Practitioner practicing in Millsboro, DE. With approximately 10 years of clinical experience since completing medical education in 2016, Angela Knotts delivers high-quality medical care to the local community at 231 S WASHINGTON ST.

Angela Knotts maintains professional affiliations with Advanced Pain Management Specialists Llc, Talis Healthcare Llc and accepts Medicare assignment.

Frequently performed procedures and clinical services include injection, ocrelizumab, 1 mg, injection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mg, injection, eptinezumab-jjmr, 1 mg. Full Medicare procedure pricing transparency rates and service volume details are listed on this profile.

Practice Location & Contact Primary Location

Practice Address

231 S Washington St

Millsboro, DE 199661236

Telephone 6095851122

Fax 6095850309

Associated Practice Facility / Clinic

🏢 Green Valley Terrace Snf Llc Facility NPI 1730142803

Medicare Profile & Education

Medical School

Other

Graduation Year

2016

Medicare Assignment

✓ Accepts Assignment

Telehealth Flag

In-Person Only

Specialty Benchmarks & Practice Insights

Comparative analytics for Nurse Practitioner in Millsboro, DE

Established Specialist (10-20 Yrs)

Practitioner Clinical Experience

10 Yrs +1.6 yrs vs City Avg

City Avg: 8.4 Yrs

State Avg: 9.1 Yrs

Regional Practice Density

21 Specialists

Practicing in Millsboro, DE (552 Statewide)

Telehealth Adoption Rate

33.3% Regional Adoption

In-Person Office Visits Only

Medicare Pricing Discount

76.8% Avg Savings

Under CMS Medicare Fee Schedule vs Standard Submitted Charges

Clinical Seniority & Experience Comparison

Dr. Knotts (10 Years) 10 Yrs

Millsboro Specialty Average (8.4 Years) 8.4 Yrs

Performed Procedures & Service Volume

Top Medicare Part B procedures performed by this practitioner

CMS Official Data (2024)

Reporting Year:

HCPCS Code & Description	Services	Patients	Submitted Charge	Medicare Allowed
J2350 Injection, ocrelizumab, 1 mg	14,100	19	$149.31	$55.99
J1561 Injection, immune globulin, (gamunex-c/gammaked), non-lyophilized (e.g., liquid), 500 mg	13,461	18	$163.16	$48.48
J3032 Injection, eptinezumab-jjmr, 1 mg	11,000	17	$44.07	$18.13
J0129 Injection, abatacept, 10 mg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered)	7,025	14	$127.97	$42.57
J1745 Injection, infliximab, excludes biosimilar, 10 mg	6,636	23	$250.78	$31.34
J0897 Injection, denosumab, 1 mg	5,820	68	$68.77	$25.35
J2919 Injection, methylprednisolone sodium succinate, 5 mg	5,284	48	$0.80	$0.29
J9312 Injection, rituximab, 10 mg	3,320	14	$219.60	$77.07
96413 Infusion of chemotherapy into a vein up to 1 hour	504	114	$395.07	$107.76
96365 Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less	485	97	$191.16	$51.84
96366 Infusion into a vein for therapy, prevention, or diagnosis, each additional hour	406	35	$59.91	$16.89
96401 Administration of non-hormonal anti-neoplastic chemotherapy under skin or into muscle	274	88	$220.69	$59.41
96415 Administration of chemotherapy into vein, each additional hour	248	72	$83.17	$23.00
96375 Injection of additional new drug or substance into vein	206	65	$46.07	$12.81
J3489 Injection, zoledronic acid, 1 mg	197	41	$212.49	$6.39
J1200 Injection, diphenhydramine hcl, up to 50 mg	77	41	$3.09	$0.82
J2930 Injection, methylprednisolone sodium succinate, up to 125 mg	74	20	$16.41	$5.82
96372 Injection beneath the skin or into muscle for therapy, diagnosis, or prevention	51	12	$42.93	$11.93
99213 Established patient office or other outpatient visit, typically 15 minutes	48	46	$424.58	$77.10
99214 Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more	43	41	$600.00	$106.80
96374 Injection of drug or substance into a vein for therapy, diagnosis, or prevention	28	26	$109.05	$30.67
G0481 Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms	17	17	$703.53	$153.46
80307 Testing for presence of drug, by chemistry analyzers	16	16	$280.00	$60.90

HCPCS Code & Description	Services	Patients	Submitted Charge	Medicare Allowed
96366 Infusion into a vein for therapy, prevention, or diagnosis, each additional hour	206	21	$34.78	$17.53
96365 Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less	173	40	$120.06	$55.38
99213 Established patient office or other outpatient visit, typically 15 minutes	89	86	$420.56	$78.00
99214 Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more	64	61	$600.00	$109.98
80307 Testing for presence of drug, by chemistry analyzers	34	34	$280.00	$60.90
G0481 Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms	25	25	$700.00	$153.46
96415 Administration of chemotherapy into vein, each additional hour	20	11	$53.84	$24.13
96372 Injection beneath the skin or into muscle for therapy, diagnosis, or prevention	13	11	$47.30	$11.97
96413 Infusion of chemotherapy into a vein up to 1 hour	12	11	$298.81	$110.92

HCPCS Code & Description	Services	Patients	Submitted Charge	Medicare Allowed
99214 Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more	99	96	$620.00	$109.45
99213 Established patient office or other outpatient visit, typically 15 minutes	87	81	$440.00	$77.51
96365 Infusion into a vein for therapy, prevention, or diagnosis, 1 hour or less	79	13	$116.06	$59.86
80307 Testing for presence of drug, by chemistry analyzers	37	37	$280.00	$61.34
G0482 Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but not limited to gc/ms (any type, single or tandem) and lc/ms	26	26	$890.00	$196.37

HCPCS Code & Description	Services	Patients	Submitted Charge	Medicare Allowed
99214 Established patient office or other outpatient visit with moderate level of decision making, if using time, 30 minutes or more	424	177	$616.21	$108.69
99213 Established patient office or other outpatient visit, typically 15 minutes	86	65	$434.14	$78.93
99204 New patient office or other outpatient visit with moderate level of medical decision making, if using time, 45 minutes or more	46	46	$813.09	$145.66
J1885 Injection, ketorolac tromethamine, per 15 mg	26	13	$1.56	$0.47
96372 Injection beneath the skin or into muscle for therapy, diagnosis, or prevention	25	13	$104.24	$12.32

Medical Specialties & State Licenses

CMS Verified: 2026-03-25

Nurse Practitioner Primary Specialty

NUCC Taxonomy Code: 363L00000X

State License DE LG-0011508

(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision making and direct accountability for clinical judgment across the health care continuum or in a certified specialty. (2) A registered nurse who has completed additional training beyond basic nursing education and who provides primary health care services in accordance with state nurse practice laws or statutes. Tasks performed by nurse practitioners vary with practice requirements mandated by geographic, political, economic, and social factors. Nurse practitioner specialists include, but are not limited to, family nurse practitioners, gerontological nurse practitioners, pediatric nurse practitioners, obstetric-gynecologic nurse practitioners, and school nurse practitioners.

Hospital & Practice Group Affiliations

Advanced Pain Management Specialists Llc

655 S Bay Rd, Dover, DE 199014659

Phone: 8555277246

Talis Healthcare Llc

2 Penns Way, New Castle, DE 197202407

Phone: 8447767778

Advanced Pain Management Specialists Llc

6602 Church Hill Rd, Chestertown, MD 216202323

Phone: 4105712946

Talis Healthcare Llc

145 E Carroll St, Salisbury, MD 218015454

Phone: 4692060292

Advanced Pain Management Specialists Llc

120 Sallitt Dr, Stevensville, MD 216662154

Phone: 4105712946

Practice Associates & Co-Workers

Healthcare professionals and specialists practicing at this location or sharing practice phone/fax

40 Associated Practitioners

Brianna Malvone , PA-C

Physician Assistant

NPI 1003297201

Physician Assistant (Certified)

Dr. Ziad Alkhoury , MD

Internal Medicine

NPI 1073554796

Doctor of Medicine (M.D.)

Dr. Seth Mensah , MD

Internal Medicine

NPI 1104911197

Doctor of Medicine (M.D.)

Dr. Rupinder Chawla , MD

Internal Medicine

NPI 1114194610

Doctor of Medicine (M.D.)

Dr. Morakinyo Araoye , MD

Internal Medicine

NPI 1174939615

Doctor of Medicine (M.D.)

Dr. Thomas Drago , MD

Internal Medicine

NPI 1215678099

Doctor of Medicine (M.D.)

Career & Practice History Timeline

Chronological log of verified NPI updates, location relocations, credentials, and registry changes

11 Historical Events

📍

Updated Practice Location March 25, 2026

Registered at 231 S WASHINGTON ST, MILLSBORO, DE 199661236 (Tel: 6095851122)

📍

Updated Business Mailing Address March 25, 2026

Registered at PO BOX 7411009, CHICAGO, IL 606743009 (Tel: 6095851122)

🎓

Medical Taxonomy / Specialty Registered (Primary Specialty) March 25, 2026

Nurse Practitioner (License #LG-0011508 in DE)

📍

Updated Practice Location March 26, 2021

Registered at 1673 S STATE ST STE B, DOVER, DE 199015148 (Tel: 8555277246)

📍

Updated Business Mailing Address March 26, 2021

Registered at 2 PARK CENTER CT STE 200, OWINGS MILLS, MD 211174221 (Tel: 8555277246)

✅

NPI Profile Active November 17, 2016

NPI status registered as active in NPPES database

📍

Updated Practice Location November 17, 2016

Registered at 6095 MARSHALEE DR, SUITE 100, ELKRIDGE, MD 210756053 (Tel: 4103793532)

📍

Updated Business Mailing Address November 17, 2016

Registered at 24505 FRIENDSHIP RD, PRESTON, MD 216552464 (Tel: 4107143368)

👤

Provider Name / Credentials Updated November 17, 2016

Recorded as ANGELA KNOTTS, FNP

🎓

Medical Taxonomy / Specialty Registered (Primary Specialty) November 17, 2016

Nurse Practitioner (License #R135147 in MD)

🟢

Initial NPI Registration & Enumeration November 17, 2016

First registered as active Individual Practitioner in NPPES Database.

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NPI Administrative Meta

NPI Number: 1023550308

Entity Type:

Individual Provider Physician, Nurse Practitioner, or Solo Healthcare Professional (Type 1 NPI)

Enumeration Date: November 17, 2016

Last Update: March 25, 2026

Sole Proprietor: Yes

Update or Correct Profile

Mailing Address

Po Box 7411009

Chicago, IL 606743009

Phone: 6095851122

Public Domain Record This profile contains public domain information published by CMS and NPPES under the Freedom of Information Act (FOIA).

⚠️ Medical Disclaimer

This directory listing is for informational purposes only and does not constitute medical advice, diagnosis, or physician endorsement. If you are experiencing a medical emergency, please call 911 immediately.