Independent US Healthcare Provider Directory & Public Medical Database
Active NPI 1215998976 Individual Practitioner Male Practitioner

Dr. Mario A Santiago , MD

General Practice • Orlando, FL

✓ Accepts Medicare Assignment

Professional Overview & Biography Verified Profile Summary

Dr. Mario Santiago, MD is a certified General Practice practicing in Orlando, FL. With approximately 26 years of clinical experience since completing medical education in 2000, Dr. Santiago delivers high-quality medical care to the local community at 737 S SEMORAN BLVD.

Dr. Santiago is affiliated with Centerwell Senior Primary Care Fl Inc. and accepts Medicare assignment.

Frequently performed procedures and clinical services include established patient outpatient office visit, insertion of needle into vein for collection of blood sample. Full Medicare procedure pricing transparency rates and service volume details are listed on this profile.

Practice Location & Contact Primary Location

Practice Address

737 S Semoran Blvd

Orlando, FL 328073121

Telephone 3212474960
Associated Practice Facility / Clinic

Medicare Profile & Education

Medical School

Other

Graduation Year

2000

Medicare Assignment

✓ Accepts Assignment

Telehealth Flag

In-Person Only

Specialty Benchmarks & Practice Insights

Comparative analytics for General Practice in Orlando, FL

Senior Veteran Specialist (>20 Yrs)
Practitioner Clinical Experience
26 Yrs +2.6 yrs vs City Avg
City Avg: 23.4 Yrs
State Avg: 26.1 Yrs
Regional Practice Density
170 Specialists

Practicing in Orlando, FL (2490 Statewide)

Telehealth Adoption Rate
16.5% Regional Adoption

In-Person Office Visits Only

Medicare Pricing Discount
37.9% Avg Savings

Under CMS Medicare Fee Schedule vs Standard Submitted Charges

Clinical Seniority & Experience Comparison

Dr. Santiago (26 Years) 26 Yrs
Orlando Specialty Average (23.4 Years) 23.4 Yrs

Performed Procedures & Service Volume

Top Medicare Part B procedures performed by this practitioner

CMS Official Data (2020)
Reporting Year:
HCPCS Code & Description Services Patients Submitted Charge Medicare Allowed
99213 Established patient office or other outpatient visit, typically 15 minutes
28 24 $125.50 $77.89

Medical Specialties & State Licenses

CMS Verified: 2026-02-17
General Practice Primary Specialty

NUCC Taxonomy Code: 208D00000X

State License FL ACN648

A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.

General Practice

NUCC Taxonomy Code: 208D00000X

State License PR 14652

A physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.

Additional State Medicaid & Healthcare Payer Identifiers

Medicaid State Provider ID
101875500 (FL)
Commercial Insurance / Payer ID Medicare
N0716 (FL)

Hospital & Practice Group Affiliations

Centerwell Senior Primary Care Fl Inc.

737 S Semoran Blvd, Orlando, FL 328073121

Phone: 3212474960

Practice Associates & Co-Workers

Healthcare professionals and specialists practicing at this location or sharing practice phone/fax

7 Associated Practitioners
Dr. David Sanjuan , MD

General Practice

NPI 1306270509

Doctor of Medicine (M.D.)

Jonnathan Soltero , ARNP

Nurse Practitioner - Family

NPI 1376068940

Advanced Registered Nurse Practitioner

Alexsandra King , NP

Nurse Practitioner - Family

NPI 1407388028

Nurse Practitioner

Martha Bonett , APRN

Nurse Practitioner - Primary Care

NPI 1427827138

Advanced Practice Registered Nurse

NPI 1467566711

Doctor of Medicine (M.D.)

Dr. Jorge Torres , MD

General Practice

NPI 1497189971

Doctor of Medicine (M.D.)

Career & Practice History Timeline

Chronological log of verified NPI updates, location relocations, credentials, and registry changes

16 Historical Events
📍
Updated Business Mailing Address March 21, 2025

Registered at 6101 BLUE LAGOON DR STE 200, MIAMI, FL 331263168 (Tel: 3055002000)

📍
Updated Practice Location March 06, 2025

Registered at 737 S SEMORAN BLVD, ORLANDO, FL 328073121 (Tel: 3212474960)

📍
Updated Business Mailing Address March 06, 2025

Registered at 6101 BLUE LAGOON DR STE 400, MIAMI, FL 331262051 (Tel: 3055002000)

📍
Updated Practice Location November 16, 2022

Registered at 1303 S SEMORAN BLVD, ORLANDO, FL 328072915 (Tel: 3055340076)

🎓
Medical Taxonomy / Specialty Registered (Primary Specialty) November 16, 2022

General Practice (License #14652 in PR)

🎓
Medical Taxonomy / Specialty Registered (Primary Specialty) September 07, 2021

General Practice (License #ACN648 in FL)

📍
Updated Practice Location June 23, 2021

Registered at 4980 W 10TH AVE, HIALEAH, FL 330123437 (Tel: 3055340076)

📍
Updated Business Mailing Address June 23, 2021

Registered at 1400 NW 107TH AVE STE 500, SWEETWATER, FL 331722746 (Tel: 3055340076)

📍
Updated Practice Location May 12, 2020

Registered at 5201 HOLLYWOOD BLVD, HOLLYWOOD, FL 330216422 (Tel: 9542286619)

📍
Updated Business Mailing Address May 12, 2020

Registered at 5201 HOLLYWOOD BLVD, HOLLYWOOD, FL 330216422 (Tel: 9542286619)

NPI Profile Active July 08, 2007

NPI status registered as active in NPPES database

📍
Updated Practice Location July 08, 2007

Registered at COND PALMAR DEL RIO, AVE. ARBOLOTE BOX 462 APT. 16-05, GUAYNABO, PR 009695511 (Tel: 7874478780)

📍
Updated Business Mailing Address July 08, 2007

Registered at COND PALMAR DEL RIO, AVE. ARBOLOTE BOX 462 APT. 16-05, GUAYNABO, PR 009695511 (Tel: 7874478780)

👤
Provider Name / Credentials Updated July 08, 2007

Recorded as MARIO SANTIAGO, M.D.

🎓
Medical Taxonomy / Specialty Registered (Primary Specialty) July 08, 2007

General Practice (License #14652 in PR)

🟢
Initial NPI Registration & Enumeration March 31, 2006

First registered as active Individual Practitioner in NPPES Database.

Patient & Community Reviews

Verified patient ratings, medical care experiences, and facility photos

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NPI Administrative Meta

NPI Number: 1215998976
Entity Type:
Individual Provider Physician, Nurse Practitioner, or Solo Healthcare Professional (Type 1 NPI)
Enumeration Date: March 31, 2006
Last Update: February 17, 2026
Sole Proprietor: No

Mailing Address

6101 Blue Lagoon Dr Ste 200

Miami, FL 331263168

Phone: 3055002000

Public Domain Record This profile contains public domain information published by CMS and NPPES under the Freedom of Information Act (FOIA).
⚠️ Medical Disclaimer

This directory listing is for informational purposes only and does not constitute medical advice, diagnosis, or physician endorsement. If you are experiencing a medical emergency, please call 911 immediately.